The Histone H2B (Acetyl K15) monoclonal Antibody from Bioss Inc. is a Mouse Monoclonal antibody to H2B clustered histone 3, and H2BC3. This antibody recognizes Human antigen. The Histone H2B (Acetyl K15) monoclonal Antibody has been validated for the following applications: Western Blot.
Description
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Jul 2008]